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: Tobacco use can interfere with estrogen therapy. It is known to potentially lower the effectiveness of oral estrogen and significantly increase the risk of dangerous blood clots.

: Like all smokers, transgender individuals face increased risks of various cancers (lung, mouth, throat), respiratory diseases, and heart disease. Support and Resources

: Approximately 36% of TGE adults smoke cigarettes, compared to 21% of heterosexual cisgender adults.

Overview of feminizing hormone therapy - UCSF Transgender Care

Smoking poses unique health risks for transgender women, particularly those undergoing .