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An isolated prolongation of the activated partial thromboplastin time (aPTT) that does not correct when mixed with normal plasma.

Used to stop active bleeding by circumventing the inhibited Factor VIII.

Sudden, severe bruising (ecchymosis), mucosal bleeding, or prolonged bleeding after delivery.

High-dose corticosteroids (Prednisone) are the standard first step, sometimes combined with Cyclophosphamide or Rituximab.