Mayuri slowly drives his Zanpakutō into Szayelaporro's heart. Due to the drug, the villain experiences the agony of the blade piercing him for what feels like hundreds of years.
After being swallowed by Mayuri’s Bankai, Szayelaporro uses his "Gabriel" technique to impregnate Mayuri's lieutenant, Nemu, and resurrect himself through her body by absorbing her spiritual particles. Bleach (Dub) Episode 199
Mayuri reveals he anticipated this move and placed various drugs inside Nemu. By resurrecting through her, Szayelaporro accidentally ingests a "Superhuman Drug". Szayelaporro accidentally ingests a "Superhuman Drug".