Martin Luther participated in the Leipzig Debate against Johann Eck , furthering the break with the Roman Catholic Church.

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The events starting in 1519 portrayed a significant, violent clash between Spanish invaders and the Aztec civilization, often depicted as a struggle between Spanish power and Aztec resistance.

Benzyl alcohol, a food additive re-evaluated for safety by the European Food Safety Authority (EFSA).

Charles V , king of Spain, was elected Emperor, centralizing power over vast territories.